The F4F played an important role in the Battle of Midway.

A key and difficult role to fill overall during the early phases of WW2. The commentary below demonstrates the role of escorting and supporting the slower aircraft engaged in the battle. The pilot report debriefs noted that more firepower was needed in later iterations of the aircraft as they would expend ammo rapidly with 6 guns on the F4F-4 which reduced the rounds available per gun due to space constraints. Though not as nimble as its main Japanese opponent, the Mitsubishi A6M Zero, the Wildcat quickly earned a reputation for its ruggedness and ability to withstand shocking amounts of damage while still remaining airborne. Learning quickly, American pilots developed tactics to deal with the Zero which utilized the Wildcat's high service ceiling, greater ability to power dive, and heavy armament. Group tactics were also devised, such as the "Thach Weave" which allowed Wildcat formations to counter a diving attack by Japanese aircraft.

“At about 1045 commenced launching the Attack Group composed of 17 VSB, 12 VTB and 6 VF. The torpedo planes were directed to proceed immediately towards the objective; and the VSBs ordered to circle overhead for 12 minutes and then proceed to overtake the VT before reaching the enemy. In order to conserve fuel for the VF, they were launched at 1105 with orders to rendezvous enroute. Due to the slow speed of the TBD's and the small fuel capacity of the F4F-4's, the above procedure was deemed expedient and worked out very well. At 1145 all three squadrons were rendezvoused and the group took the following formation: VT-3 at 1500 feet (just below the cloud base), 2 VF for low coverage at 2500 feet, 4 VF at 5000-6000 feet to protect the VT and low VF, and VB-3 at 16,000 feet. At about 1200, the enemy force was sighted bearing 345°, distance 30-40 miles, headed on an easterly course, speed about 20 knots. It consisted of 3 or 4 carriers, 2 BB's, 4 CA's, 1 or more CL's and many DD. The formation appeared scattered; apparently the CV's had just previously landed their planes on board after their attack on Midway Island. Insofar as could be seen, the enemy CV's appeared undamaged. At about 1220 VB-3 lost contact with the torpedo planes and was unable to communicate with them by radio. At 1225, the order to attack was given by VB-3. Enclosure (C) position of enemy CV's.”

“The fighter escort group consisted of 6 F4F-4's of VF-3 squadron, their mission being to protect the torpedo planes' attack. Two VF were placed at 1000 feet above the torpedo planes and the other four VF 3000-4000 feet above them to furnish further protection. When about 4 miles from the Jap outer screen., which in turn was about 10- miles out from the CV's, two AA bursts were fired by a Jap ship. These bursts were used evidently to direct the enemy Combat Air Patrol to our planes, for almost immediately afterwards our VT and VF were attacked by about 18-20 Zero fighters. Our VF formed a line astern formation in order to stay together and give the leader an opportunity to turn and fire at the attacking planes. Soon after this the rear fighter was shot down. The formation twisted and turned to prevent the Zeros from getting on their tails and also to obtain firing position. During the engagement our remaining 3 VF were able to shoot down 5 Zeros. The Zeros concentrated most of their attacks on the rear plane, making beam and astern runs and pulling clear after each run.”

“The two VF planes directly over the torpedo planes were able to furnish considerable support to the VT during the first part of the approach when there were only 4 Zeros attacking. But later they were joined by 6 more Zeros, and the 2 VF were too heavily out-numbered to be of much help. They shot down one Zero and possibly another, and saw one Zero shot down by the TBD rear seat men. Soon thereafter, they became separated from each other and from the torpedo planes. One of these fighters was badly damaged and crash landed on board the Hornet. The 4 remaining planes of the escort group landed on board. They lost one pilot and two planes and shot down 6 and damaged two Zeros in the engagement.”"

"F4F-4 Airplanes." Battle of Midway Action Report, USS Yorktown (CV-5). Retrieved: 22 October 2010.